node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHM18430.1 | SHM28283.1 | SAMN05660826_00420 | SAMN05660826_00664 | Protein translocase subunit yidC. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.988 |
SHM18430.1 | SHM52931.1 | SAMN05660826_00420 | SAMN05660826_01279 | Protein translocase subunit yidC. | Protein translocase subunit yajC. | 0.919 |
SHM18430.1 | ffh | SAMN05660826_00420 | SAMN05660826_00215 | Protein translocase subunit yidC. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.927 |
SHM18430.1 | ftsY | SAMN05660826_00420 | SAMN05660826_00213 | Protein translocase subunit yidC. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.918 |
SHM18430.1 | pheT | SAMN05660826_00420 | SAMN05660826_00302 | Protein translocase subunit yidC. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.602 |
SHM18430.1 | secA | SAMN05660826_00420 | SAMN05660826_01417 | Protein translocase subunit yidC. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.935 |
SHM18430.1 | secD | SAMN05660826_00420 | SAMN05660826_01276 | Protein translocase subunit yidC. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.989 |
SHM18430.1 | secE | SAMN05660826_00420 | SAMN05660826_01707 | Protein translocase subunit yidC. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.978 |
SHM18430.1 | secF | SAMN05660826_00420 | SAMN05660826_01275 | Protein translocase subunit yidC. | Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.963 |
SHM18430.1 | secY | SAMN05660826_00420 | SAMN05660826_02163 | Protein translocase subunit yidC. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.991 |
SHM28283.1 | SHM18430.1 | SAMN05660826_00664 | SAMN05660826_00420 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit yidC. | 0.988 |
SHM28283.1 | SHM52931.1 | SAMN05660826_00664 | SAMN05660826_01279 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit yajC. | 0.923 |
SHM28283.1 | ffh | SAMN05660826_00664 | SAMN05660826_00215 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.981 |
SHM28283.1 | ftsY | SAMN05660826_00664 | SAMN05660826_00213 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.985 |
SHM28283.1 | pheT | SAMN05660826_00664 | SAMN05660826_00302 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.502 |
SHM28283.1 | secA | SAMN05660826_00664 | SAMN05660826_01417 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.992 |
SHM28283.1 | secD | SAMN05660826_00664 | SAMN05660826_01276 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.984 |
SHM28283.1 | secE | SAMN05660826_00664 | SAMN05660826_01707 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.997 |
SHM28283.1 | secF | SAMN05660826_00664 | SAMN05660826_01275 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.922 |
SHM28283.1 | secY | SAMN05660826_00664 | SAMN05660826_02163 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.993 |