STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
thiCHydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (432 aa)    
Predicted Functional Partners:
SHM19130.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 0.997
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.994
SHM18135.1
2-iminoacetate synthase.
  
 0.969
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
  
 
 0.943
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
     
 0.874
SHM62691.1
Molybdopterin or thiamine biosynthesis adenylyltransferase.
 
  
 0.738
SHM27520.1
Sulfur carrier protein.
  
  
 0.708
SHM34152.1
Sulfur carrier protein.
  
  
 0.708
SHM36809.1
Molybdopterin converting factor, small subunit.
  
  
 0.708
SHM72324.1
Molybdopterin or thiamine biosynthesis adenylyltransferase.
  
  
 0.690
Your Current Organism:
Caldanaerovirga acetigignens
NCBI taxonomy Id: 447595
Other names: C. acetigignens, Caldanaerovirga acetigignens Wagner et al. 2009, DSM 18802, strain JW/SA-NV4
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