Lery_0103 protein (Legionella erythra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

Lery_0103

Methyltransferase, ubiE/COQ5 family. (252 aa)

Predicted Functional Partners:

Lery_0104

0.746

Lery_0105

0.746

Lery_2866

0.662

Lery_2856

0.577

Lery_2728

0.499

ribA

0.498

Lery_0106

0.487

grpB

0.474

Lery_0796

0.430

Lery_0359

0.422

Your Current Organism:

Legionella erythra

NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lery_0103	Lery_0104	Lery_0103	Lery_0104	Methyltransferase, ubiE/COQ5 family.	Glyoxalase-like domain protein.	0.746
Lery_0103	Lery_0105	Lery_0103	Lery_0105	Methyltransferase, ubiE/COQ5 family.	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	0.746
Lery_0103	Lery_0106	Lery_0103	Lery_0106	Methyltransferase, ubiE/COQ5 family.	Hypothetical protein.	0.487
Lery_0103	Lery_0359	Lery_0103	Lery_0359	Methyltransferase, ubiE/COQ5 family.	N-acetyltransferase GCN5.	0.422
Lery_0103	Lery_0796	Lery_0103	Lery_0796	Methyltransferase, ubiE/COQ5 family.	Hypothetical protein; N-terminal GNAT family acetyltransferase.	0.430
Lery_0103	Lery_2728	Lery_0103	Lery_2728	Methyltransferase, ubiE/COQ5 family.	Guanylate cyclase.	0.499
Lery_0103	Lery_2856	Lery_0103	Lery_2856	Methyltransferase, ubiE/COQ5 family.	GNAT family acetyltransferase.	0.577
Lery_0103	Lery_2866	Lery_0103	Lery_2866	Methyltransferase, ubiE/COQ5 family.	N-acetyltransferase GCN5.	0.662
Lery_0103	grpB	Lery_0103	Lery_1604	Methyltransferase, ubiE/COQ5 family.	Glutamate rich protein GrpB.	0.474
Lery_0103	ribA	Lery_0103	Lery_0985	Methyltransferase, ubiE/COQ5 family.	Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.498
Lery_0104	Lery_0103	Lery_0104	Lery_0103	Glyoxalase-like domain protein.	Methyltransferase, ubiE/COQ5 family.	0.746
Lery_0104	Lery_0105	Lery_0104	Lery_0105	Glyoxalase-like domain protein.	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	0.788
Lery_0104	Lery_0106	Lery_0104	Lery_0106	Glyoxalase-like domain protein.	Hypothetical protein.	0.503
Lery_0105	Lery_0103	Lery_0105	Lery_0103	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	Methyltransferase, ubiE/COQ5 family.	0.746
Lery_0105	Lery_0104	Lery_0105	Lery_0104	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	Glyoxalase-like domain protein.	0.788
Lery_0105	Lery_0106	Lery_0105	Lery_0106	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	Hypothetical protein.	0.503
Lery_0106	Lery_0103	Lery_0106	Lery_0103	Hypothetical protein.	Methyltransferase, ubiE/COQ5 family.	0.487
Lery_0106	Lery_0104	Lery_0106	Lery_0104	Hypothetical protein.	Glyoxalase-like domain protein.	0.503
Lery_0106	Lery_0105	Lery_0106	Lery_0105	Hypothetical protein.	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	0.503
Lery_0359	Lery_0103	Lery_0359	Lery_0103	N-acetyltransferase GCN5.	Methyltransferase, ubiE/COQ5 family.	0.422