Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lery_0124UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1079 aa)    
Predicted Functional Partners:
Lery_0395
Recombinase B.
 
 
 0.996
Lery_2187
Putative conjugative transfer protein TraI.
  
 0.989
lysAC
Bifunctional aspartate kinase/diaminopimelate decarboxylase protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
       0.874
traA_1
Conjugal transfer protein TraA.
  
 0.870
Lery_1714
Hypothetical protein.
  
 0.870
Lery_1715
Hypothetical protein.
  
 0.870
uvrD
DNA helicase II.
    
0.745
Lery_0126
Long chain fatty acid transporter.
 
     0.740
Lery_0166
TraI.
  
 0.703
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.702
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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