Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_0236Hypothetical protein; Alpha-2-macroglobulin family N-terminal region. (1919 aa)    
Predicted Functional Partners:
Lery_0235
Penicillin binding protein 1C, peptidoglycan biosynthesis.
   
 0.981
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.636
Lery_1556
Hypothetical protein.
  
    0.545
Lery_0466
IcmF.
  
    0.519
Lery_0234
Hypothetical protein.
   
  0.509
iraA
Small-molecule methyltransferase IraA.
  
     0.493
yjeA
Endo-1,4-beta-xylanase.
  
 
   0.492
Lery_0779
Hypothetical protein.
  
     0.487
Lery_0465
IcmH (DotU).
  
    0.468
Lery_1668
Polyketide synthase module.
 
 
 0.460
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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