STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilZ_1Type IV pilus assembly PilZ. (185 aa)    
Predicted Functional Partners:
Lery_0656
GGDEF domain-containing sensory box protein.
 
 
 0.853
fliD
Flagellar hook associated protein 2 FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
    0.835
Lery_1127
Flagellar protein FliS.
 
  
 0.830
Lery_0969
GGDEF domain-containing sensory box protein.
  
 
 0.827
Lery_2896
Regulatory protein (GGDEF and EAL domains).
  
 
 0.827
stuC
Sensor histidine kinase.
  
 
 0.822
Lery_0432
GGDEF domain-containing sensory box protein.
  
 
 0.805
Lery_0948
Inner membrane protein/sensory box protein LssE.
  
 
 0.800
flgK
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
 
  
 0.793
Lery_0749
Regulatory protein (GGDEF, PAS, PAC domains).
   
 
 0.769
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (28%) [HD]