uptC protein (Legionella erythra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

uptC

Type II secretion system protein. (372 aa)

Predicted Functional Partners:

Lery_1110

0.856

pilM

0.856

pilC

0.822

lspF

0.790

Lery_0391

0.755

pilQ

0.745

Lery_0395

0.726

Lery_0393

0.662

pilN

0.633

Lery_2075

0.631

Your Current Organism:

Legionella erythra

NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lery_0391	Lery_0393	Lery_0391	Lery_0393	Cardiac ankyrin repeat-containing protein.	Hypothetical protein.	0.637
Lery_0391	Lery_0395	Lery_0391	Lery_0395	Cardiac ankyrin repeat-containing protein.	Recombinase B.	0.610
Lery_0391	uptC	Lery_0391	Lery_0392	Cardiac ankyrin repeat-containing protein.	Type II secretion system protein.	0.755
Lery_0393	Lery_0391	Lery_0393	Lery_0391	Hypothetical protein.	Cardiac ankyrin repeat-containing protein.	0.637
Lery_0393	Lery_0395	Lery_0393	Lery_0395	Hypothetical protein.	Recombinase B.	0.856
Lery_0393	uptC	Lery_0393	Lery_0392	Hypothetical protein.	Type II secretion system protein.	0.662
Lery_0395	Lery_0391	Lery_0395	Lery_0391	Recombinase B.	Cardiac ankyrin repeat-containing protein.	0.610
Lery_0395	Lery_0393	Lery_0395	Lery_0393	Recombinase B.	Hypothetical protein.	0.856
Lery_0395	uptC	Lery_0395	Lery_0392	Recombinase B.	Type II secretion system protein.	0.726
Lery_1110	Lery_2075	Lery_1110	Lery_2075	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type IV pilus biogenesis protein PilO.	0.653
Lery_1110	lspF	Lery_1110	Lery_1153	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type II secretory pathway protein LspF.	0.934
Lery_1110	pilC	Lery_1110	Lery_1111	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Pilus assembly protein PilC.	0.989
Lery_1110	pilM	Lery_1110	Lery_2077	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Tfp pilus assembly protein, ATPase PilM.	0.776
Lery_1110	pilN	Lery_1110	Lery_2076	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Tfp pilus assembly protein PilN.	0.599
Lery_1110	pilQ	Lery_1110	Lery_2073	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type IV pilus (Tfp) assembly protein PilQ.	0.693
Lery_1110	uptC	Lery_1110	Lery_0392	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type II secretion system protein.	0.856
Lery_2075	Lery_1110	Lery_2075	Lery_1110	Type IV pilus biogenesis protein PilO.	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.653
Lery_2075	lspF	Lery_2075	Lery_1153	Type IV pilus biogenesis protein PilO.	Type II secretory pathway protein LspF.	0.605
Lery_2075	pilC	Lery_2075	Lery_1111	Type IV pilus biogenesis protein PilO.	Pilus assembly protein PilC.	0.731
Lery_2075	pilM	Lery_2075	Lery_2077	Type IV pilus biogenesis protein PilO.	Tfp pilus assembly protein, ATPase PilM.	0.995