Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepAAminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (483 aa)    
Predicted Functional Partners:
holC
DNA polymerase III subunit chi.
  
  
 0.898
pepN
Aminopeptidase.
   
 0.890
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
   
 
 0.886
Lery_0420
Aminopeptidase; Belongs to the peptidase M17 family.
  
  
 
0.876
Lery_2526
Gamma-glutamyltranspeptidase.
     
 0.875
Lery_2239
Aspartate aminotransferase.
   
  0.864
cysK
Cystathionine beta synthase.
    
  0.859
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.849
metB
Cystathionine beta-lyase.
   
 
  0.843
gshA
Glutamate--cysteine ligase.
     
  0.842
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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