Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ahpDAlkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (171 aa)    
Predicted Functional Partners:
Lery_0463
Alkylhydroperoxide reductase, AhpC/TSA family.
 
  
 0.963
oxyR
DNA-binding transcriptional dual regulator; Belongs to the LysR transcriptional regulatory family.
 
   
 0.813
cysC
Elongation factor Tu (EF-Tu); Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
   
    0.697
Lery_1562
Carboxymuconolactone decarboxylase family transporter; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
    
 0.628
Lery_1668
Polyketide synthase module.
 
  
 0.611
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
      
 0.575
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.535
ahpC
Alkyl hydroperoxide reductase.
  
  
 0.516
Lery_1999
Glutamate synthetase.
  
 
  0.493
Lery_0464
Hypothetical protein.
       0.481
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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