Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lery_0488Putative integral inner membrane protein. (226 aa)    
Predicted Functional Partners:
merA1_2
Mercuric reductase.
 
  
 0.804
Lery_2467
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
     
  0.699
Lery_0487
Hypothetical protein.
       0.606
Lery_2258
Pyridine nucleotide-disulfide oxidoreductase.
    
 0.557
Lery_1945
2-acylglycerophosphoethanolamine acyltransferase.
    
 0.540
Lery_1856
Dihydrolipoamide dehydrogenase.
    
 0.536
gcsA
Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
   
 
  0.529
Lery_1070
Branched-chain alpha-keto acid dehydrogenase subunit E2.
     
  0.511
Lery_1855
Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
  0.511
sucB
Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
     
  0.511
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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