ykoU protein (Legionella erythra) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Legionella erythra

NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lery_0561	ykoU	Lery_0561	Lery_0562	Transmembrane protein.	Putative ATP-dependent DNA ligase YkoU.	0.701
Lery_0561	ykoV	Lery_0561	Lery_0563	Transmembrane protein.	Putative DNA repair protein YkoV; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.494
Lery_0567	ykoU	Lery_0567	Lery_0562	Low affinity iron permease.	Putative ATP-dependent DNA ligase YkoU.	0.631
Lery_0567	ykoV	Lery_0567	Lery_0563	Low affinity iron permease.	Putative DNA repair protein YkoV; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.423
Lery_0580	Lery_1213	Lery_0580	Lery_1213	Hypothetical protein.	Eukaryotic DNA topoisomerase I, catalytic core.	0.429
Lery_0580	ykoU	Lery_0580	Lery_0562	Hypothetical protein.	Putative ATP-dependent DNA ligase YkoU.	0.649
Lery_1213	Lery_0580	Lery_1213	Lery_0580	Eukaryotic DNA topoisomerase I, catalytic core.	Hypothetical protein.	0.429
Lery_1213	Lery_1901	Lery_1213	Lery_1901	Eukaryotic DNA topoisomerase I, catalytic core.	Beta-lactamase superfamily domain protein.	0.460
Lery_1213	dnaN	Lery_1213	Lery_2814	Eukaryotic DNA topoisomerase I, catalytic core.	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	0.724
Lery_1213	polA	Lery_1213	Lery_0793	Eukaryotic DNA topoisomerase I, catalytic core.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.437
Lery_1213	ykoU	Lery_1213	Lery_0562	Eukaryotic DNA topoisomerase I, catalytic core.	Putative ATP-dependent DNA ligase YkoU.	0.859
Lery_1213	ykoV	Lery_1213	Lery_0563	Eukaryotic DNA topoisomerase I, catalytic core.	Putative DNA repair protein YkoV; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.	0.748
Lery_1901	Lery_1213	Lery_1901	Lery_1213	Beta-lactamase superfamily domain protein.	Eukaryotic DNA topoisomerase I, catalytic core.	0.460
Lery_1901	polA	Lery_1901	Lery_0793	Beta-lactamase superfamily domain protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.529
Lery_1901	ykoU	Lery_1901	Lery_0562	Beta-lactamase superfamily domain protein.	Putative ATP-dependent DNA ligase YkoU.	0.685
dnaN	Lery_1213	Lery_2814	Lery_1213	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Eukaryotic DNA topoisomerase I, catalytic core.	0.724
dnaN	ligA	Lery_2814	Lery_2652	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.	0.566
dnaN	polA	Lery_2814	Lery_0793	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.993
dnaN	recA	Lery_2814	Lery_0135	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.934
dnaN	ykoU	Lery_2814	Lery_0562	DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]	Putative ATP-dependent DNA ligase YkoU.	0.914