Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icmVIntracellular multiplication protein IcmV. (152 aa)    
Predicted Functional Partners:
icmW
Intracellular multiplication protein IcmW.
     
 0.889
Lery_0619
IcmX (IcmY).
     
 0.889
Lery_0616
DotA.
       0.866
Lery_0465
IcmH (DotU).
      
 0.589
Lery_0466
IcmF.
      
 0.589
Lery_0476
Protein IcmL (DotI).
      
 0.589
icmM/dotJ
Component of the Dot/Icm secretion system, predicted inner membrane protein.
      
 0.589
icmQ
IcmQ protein.
      
 0.589
Lery_0068
Outer membrane protein TolC.
      
 0.428
Lery_1574
Dienelactone hydrolase family protein.
       0.420
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (14%) [HD]