Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
folBDihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (112 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.
 
 
 0.990
folP
7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.989
folE
GTP cyclohydrolase I.
  
 
 0.967
folC
Bifunctional protein FolC; Belongs to the folylpolyglutamate synthase family.
  
 
 0.822
Lery_0686
Hypothetical protein.
       0.569
folA
Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.562
hemE_1
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
    0.471
Lery_0491
4-amino-4-deoxychorismate lyase.
 
 
 0.455
Lery_0689
Alpha/beta hydrolase.
       0.418
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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