Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pilTTwitching motility protein PilT. (344 aa)    
Predicted Functional Partners:
Lery_1110
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.825
pilC
Pilus assembly protein PilC.
 
   
 0.809
lspF
Type II secretory pathway protein LspF.
 
   
 0.787
pilM
Tfp pilus assembly protein, ATPase PilM.
 
   
 0.748
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.737
Lery_0704
Pyridoxal-5'-phosphate dependent enzyme family transporter protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.737
stuC
Sensor histidine kinase.
  
  
 0.650
pilB
Pilus assembly protein PilB.
 
 
0.633
lspE
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 
0.628
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
   
 0.622
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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