STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilTTwitching motility protein PilT. (344 aa)    
Predicted Functional Partners:
Lery_1110
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.809
pilC
Pilus assembly protein PilC.
 
   
 0.802
lspF
Type II secretory pathway protein LspF.
 
   
 0.779
pilM
Tfp pilus assembly protein, ATPase PilM.
 
   
 0.725
pilB
Pilus assembly protein PilB.
 
 
0.678
lspE
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 
0.674
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.590
Lery_0704
Pyridoxal-5'-phosphate dependent enzyme family transporter protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.590
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
   
 0.586
comA
DNA uptake/competence protein ComA.
     
 0.493
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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