tesA protein (Legionella erythra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tesA

Esterase TesA precursor. (166 aa)

Predicted Functional Partners:

Lery_0736

0.982

Lery_0737

0.960

eglS

0.821

Lery_2847

0.821

Lery_1668

0.776

fadB

0.715

yfcX

0.715

birA

0.575

Lery_2396

0.557

msrA

0.553

Your Current Organism:

Legionella erythra

NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lery_0736	Lery_0737	Lery_0736	Lery_0737	FtsX-like permease family protein.	ABC transporter ATP binding protein.	0.991
Lery_0736	tesA	Lery_0736	Lery_0738	FtsX-like permease family protein.	Esterase TesA precursor.	0.982
Lery_0737	Lery_0736	Lery_0737	Lery_0736	ABC transporter ATP binding protein.	FtsX-like permease family protein.	0.991
Lery_0737	tesA	Lery_0737	Lery_0738	ABC transporter ATP binding protein.	Esterase TesA precursor.	0.960
Lery_1668	Lery_2847	Lery_1668	Lery_2847	Polyketide synthase module.	Chitinase.	0.443
Lery_1668	birA	Lery_1668	Lery_2931	Polyketide synthase module.	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	0.788
Lery_1668	fadB	Lery_1668	Lery_1142	Polyketide synthase module.	3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
Lery_1668	msrA	Lery_1668	Lery_0740	Polyketide synthase module.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.679
Lery_1668	tesA	Lery_1668	Lery_0738	Polyketide synthase module.	Esterase TesA precursor.	0.776
Lery_1668	yfcX	Lery_1668	Lery_1745	Polyketide synthase module.	Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
Lery_2396	Lery_2847	Lery_2396	Lery_2847	Exported membrane protein.	Chitinase.	0.591
Lery_2396	eglS	Lery_2396	Lery_0791	Exported membrane protein.	Endoglucanase precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.518
Lery_2396	tesA	Lery_2396	Lery_0738	Exported membrane protein.	Esterase TesA precursor.	0.557
Lery_2847	Lery_1668	Lery_2847	Lery_1668	Chitinase.	Polyketide synthase module.	0.443
Lery_2847	Lery_2396	Lery_2847	Lery_2396	Chitinase.	Exported membrane protein.	0.591
Lery_2847	eglS	Lery_2847	Lery_0791	Chitinase.	Endoglucanase precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.888
Lery_2847	tesA	Lery_2847	Lery_0738	Chitinase.	Esterase TesA precursor.	0.821
birA	Lery_1668	Lery_2931	Lery_1668	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	Polyketide synthase module.	0.788
birA	tesA	Lery_2931	Lery_0738	biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.	Esterase TesA precursor.	0.575
eglS	Lery_2396	Lery_0791	Lery_2396	Endoglucanase precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	Exported membrane protein.	0.518