Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lery_0764Signal transduction protein (EAL/GGDEF domain protein). (360 aa)    
Predicted Functional Partners:
Lery_2155
Putative regulatory protein (GGDEF domain).
 0.905
Lery_2415
Diguanylate kinase.
 0.885
Lery_2270
Sensor histidine kinase.
 
  
 0.871
Lery_0573
Sensor histidine kinase.
 
  
 0.865
Lery_1701
GGDEF/EAL domain-containing sensory box protein.
 
  
 0.859
Lery_1410
Sensory box protein.
 
 0.858
Lery_0749
Regulatory protein (GGDEF, PAS, PAC domains).
 
 0.853
Lery_1998
GGDEF domain-containing protein.
 
  
 0.821
Lery_0544
Regulatory protein (GGDEF and EAL domains).
  
 
  0.788
cyaA_1
Fused adenylate cyclase/two component hybrid sensor/regulator.
 
  
 0.764
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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