Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Lery_08293-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (296 aa)    
Predicted Functional Partners:
Lery_2681
Enoyl-CoA hydratase/carnithine racemase.
 
 0.996
acsB
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.979
mmsA
Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase.
 
 
 0.978
Lery_1177
Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.886
Lery_2680
3-hydroxyisobutyryl-CoA hydrolase.
  
 
 0.866
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
 0.860
Lery_1070
Branched-chain alpha-keto acid dehydrogenase subunit E2.
     
 0.847
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.812
yfcX
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.812
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
  0.788
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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