Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_0877Fumarylacetoacetate (FAA) hydrolase family protein. (422 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase.
 
 
 0.961
Lery_2026
Glutathione S-transferase (maleylacetoacetate isomerase).
 
 0.887
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.830
Lery_0878
Polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.727
Lery_0879
Short chain dehydrogenase/reductase family oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.713
Lery_1668
Polyketide synthase module.
  
 0.575
Lery_0435
Phenylalanine-4-hydroxylase.
 
  
 0.556
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.524
sdhA_2
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.507
sdhB
Succinate dehydrogenase iron-sulfur subunit.
    
  0.488
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.