pieE protein (Legionella erythra) - STRING interaction network

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Score

pieE

Substrate of the Dot/Icm secretion system. (575 aa)

Predicted Functional Partners:

map

0.827

rpsN

0.826

dksA

0.759

rpmB

0.709

hisI

0.653

hemD

0.567

Lery_0915

0.549

rpmG

0.534

cobN

0.497

rpmE

0.431

Your Current Organism:

Legionella erythra

NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lery_0915	pieE	Lery_0915	Lery_0916	MAPEG family protein.	Substrate of the Dot/Icm secretion system.	0.549
cobN	hemD	Lery_1658	Lery_1659	Aerobic cobaltochelatase subunit CobN.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.863
cobN	pieE	Lery_1658	Lery_0916	Aerobic cobaltochelatase subunit CobN.	Substrate of the Dot/Icm secretion system.	0.497
dksA	hisI	Lery_0444	Lery_0995	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.	0.589
dksA	pieE	Lery_0444	Lery_0916	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Substrate of the Dot/Icm secretion system.	0.759
dksA	rpmE	Lery_0444	Lery_1514	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	50S ribosomal protein L31; Binds the 23S rRNA.	0.471
hemD	cobN	Lery_1659	Lery_1658	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Aerobic cobaltochelatase subunit CobN.	0.863
hemD	pieE	Lery_1659	Lery_0916	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Substrate of the Dot/Icm secretion system.	0.567
hisI	dksA	Lery_0995	Lery_0444	phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.589
hisI	pieE	Lery_0995	Lery_0916	phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.	Substrate of the Dot/Icm secretion system.	0.653
hisI	rpmE	Lery_0995	Lery_1514	phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.	50S ribosomal protein L31; Binds the 23S rRNA.	0.667
map	pieE	Lery_1034	Lery_0916	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Substrate of the Dot/Icm secretion system.	0.827
map	rpsN	Lery_1034	Lery_1456	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	30S ribosomal protein S14.	0.981
pieE	Lery_0915	Lery_0916	Lery_0915	Substrate of the Dot/Icm secretion system.	MAPEG family protein.	0.549
pieE	cobN	Lery_0916	Lery_1658	Substrate of the Dot/Icm secretion system.	Aerobic cobaltochelatase subunit CobN.	0.497
pieE	dksA	Lery_0916	Lery_0444	Substrate of the Dot/Icm secretion system.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.759
pieE	hemD	Lery_0916	Lery_1659	Substrate of the Dot/Icm secretion system.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.567
pieE	hisI	Lery_0916	Lery_0995	Substrate of the Dot/Icm secretion system.	phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.	0.653
pieE	map	Lery_0916	Lery_1034	Substrate of the Dot/Icm secretion system.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.827
pieE	rpmB	Lery_0916	Lery_1318	Substrate of the Dot/Icm secretion system.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.709