Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilSSensor protein PilS. (529 aa)    
Predicted Functional Partners:
pilR
Two component response regulator PilR.
 
 0.994
Lery_0576
Sensory box histidine kinase/response regulator.
  
 0.966
stuC
Sensor histidine kinase.
  
 0.945
Lery_2143
Sensory histidine-kinase / response regulator.
 
 0.941
Lery_0946
Sensory box histidine kinase/response regulator.
 
0.903
gacS/letS
Transmission sensor LetS.
 
 0.893
rpoN
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.877
Lery_2464
Response regulator receiver domain protein.
   
 0.860
Lery_2415
Diguanylate kinase.
   
 0.836
Lery_2467
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
   
 0.819
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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