Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilCPilus assembly protein PilC. (406 aa)    
Predicted Functional Partners:
pilB
Pilus assembly protein PilB.
 
 
 0.997
Lery_1110
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.989
lspE
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 
 0.962
pilM
Tfp pilus assembly protein, ATPase PilM.
 
 
 
 0.865
uptC
Type II secretion system protein.
  
   
 0.822
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
 
 
 0.816
pilT
Twitching motility protein PilT.
 
   
 0.809
Lery_0615
DotB.
 
   
 0.799
comA
DNA uptake/competence protein ComA.
  
  
 0.792
lspG
Type II secretory pathway protein LspG.
 
  
 0.756
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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