STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lery_1113Methyl-transferase. (248 aa)    
Predicted Functional Partners:
Lery_1668
Polyketide synthase module.
   
 0.853
ispB_2
Octaprenyl-diphosphate synthase.
  
 
 0.759
Lery_1945
2-acylglycerophosphoethanolamine acyltransferase.
  
  
 0.727
cysC
Elongation factor Tu (EF-Tu); Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
  
 
 0.726
bioI
Biotin biosynthesis cytochrome P450.
    
 0.718
rlpB
Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
  
     0.714
Lery_1114
Hypothetical protein.
       0.624
Lery_2117
Transmembrane protein.
  
     0.571
gshA
Glutamate--cysteine ligase.
  
     0.556
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
  
     0.546
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.