Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_1437enoyl-ACP reductase. (251 aa)    
Predicted Functional Partners:
Lery_1668
Polyketide synthase module.
 
 0.965
Lery_1431
Hypothetical protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  0.942
Lery_1432
Hypothetical protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  0.936
fabF_1
3-oxoacyl-ACP synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  0.889
fabF_2
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
  0.871
fabZ
(3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
   
 
  0.845
lipB
Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
     
  0.842
Lery_2340
Oxidoreductase dehydrogenase, short chain; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.741
yueD
Sepiapterin reductase.
  
     0.723
acpP_2
Acyl carrier protein.
 
  0.720
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (24%) [HD]