STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaA_2Fused adenylate cyclase/two component hybrid sensor/regulator. (345 aa)    
Predicted Functional Partners:
Lery_2143
Sensory histidine-kinase / response regulator.
 0.989
Lery_2155
Putative regulatory protein (GGDEF domain).
 0.982
gacS/letS
Transmission sensor LetS.
 
 0.979
Lery_2896
Regulatory protein (GGDEF and EAL domains).
 0.979
Lery_0946
Sensory box histidine kinase/response regulator.
 0.977
Lery_2463
Inner membrane protein/sensory box protein LssE.
 0.969
Lery_0948
Inner membrane protein/sensory box protein LssE.
 0.953
Lery_2415
Diguanylate kinase.
 
 0.951
Lery_0546
Inner membrane protein.
 0.936
Lery_0576
Sensory box histidine kinase/response regulator.
 0.935
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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