STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lery_16812-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)    
Predicted Functional Partners:
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.843
Lery_1099
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
 0.810
Lery_1680
Cation efflux family protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.800
gap
Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.782
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.765
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 
 0.753
Lery_1682
Zip family transporter.
  
    0.736
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 0.735
Lery_1683
Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.730
Lery_2467
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.723
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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