Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cinA_2Competence damage inducible protein CinA. (368 aa)    
Predicted Functional Partners:
cinA_1
Competence-damage inducible protein CinA; Belongs to the CinA family.
  
 0.945
Lery_1691
Mechanosensitive ion channel MscS.
       0.866
Lery_1689
LicD family protein (phosphorylcholine metabolism).
       0.788
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.774
Lery_1690
HAD-superfamily hydrolase.
       0.773
Lery_1688
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
     0.763
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.725
dlpA
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein).
 
      0.633
comA
DNA uptake/competence protein ComA.
      
 0.589
Lery_1686
Pyridine nucleotide-disulfide oxidoreductase.
 
     0.570
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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