STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yycNPutative N-acetyltransferase YycN. (164 aa)    
Predicted Functional Partners:
Lery_1778
Hypothetical protein.
       0.768
hisI
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
    
  0.762
Lery_0089
Aminotransferase class-III.
    
 0.757
Lery_1099
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
  0.698
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
    
  0.696
Lery_1999
Glutamate synthetase.
    
 0.695
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
    
  0.694
cysS
Cysteine tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.658
metG
Methionyl tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.644
rfbA
Phosphomannose isomerase GDP mannose pyrophosphorylase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.643
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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