Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cyaA_3Fused adenylate cyclase/two component hybrid sensor/regulator. (414 aa)    
Predicted Functional Partners:
Lery_0946
Sensory box histidine kinase/response regulator.
 
 0.992
Lery_2143
Sensory histidine-kinase / response regulator.
 
 0.989
gacS/letS
Transmission sensor LetS.
 
 0.988
Lery_0576
Sensory box histidine kinase/response regulator.
 0.983
Lery_2896
Regulatory protein (GGDEF and EAL domains).
 
 0.983
Lery_0969
GGDEF domain-containing sensory box protein.
 
 0.977
stuC
Sensor histidine kinase.
 0.977
Lery_0412
Regulatory protein (GGDEF and EAL domains).
 
 0.973
Lery_0656
GGDEF domain-containing sensory box protein.
  
 0.973
Lery_0432
GGDEF domain-containing sensory box protein.
  
 0.967
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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