Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_1795Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family. (369 aa)    
Predicted Functional Partners:
capD
Nucleoside-diphosphate sugar epimerase.
 
 
 0.945
iolG_2
Myo-inositol 2-dehydrogenase.
 
 
 0.933
Lery_1990
Chloramphenicol acetyltransferase.
  
 0.891
pyrF
Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.866
Lery_1992
UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.808
Lery_1168
Oxidoreductase.
 
 
 0.807
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
       0.789
Lery_0185
Chloramphenicol acetyltransferase.
  
 
 0.753
fmt
Methionyl tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
 
 0.712
Lery_0141
Oxidoreductase.
  
 
 0.709
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (12%) [HD]