STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lery_1798Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)    
Predicted Functional Partners:
Lery_1668
Polyketide synthase module.
 
 0.890
rssA
Esterase of the alpha-beta hydrolase superfamily protein.
       0.798
Lery_1799
Bacteriophage-like DNA polymerase.
       0.788
Lery_0878
Polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.745
phaB_1
Acetyoacetyl CoA reductase.
  
 
  0.705
bioI
Biotin biosynthesis cytochrome P450.
  
 0.679
Lery_0223
Pteridine reductase.
  
 
  0.615
Lery_0519
Oxydoreductase.
  
 
  0.613
Lery_1004
YcaC related amidohydrolase.
  
 
  0.536
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.531
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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