Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
Lery_1994Hypothetical protein. (500 aa)    
Predicted Functional Partners:
iraA
Small-molecule methyltransferase IraA.
     
 0.833
Lery_1682
Zip family transporter.
  
 
   0.626
Lery_2539
Cysteine protease.
  
     0.563
Lery_2746
Cysteine protease.
  
     0.545
Lery_2307
Amino acid (lysine) permease.
  
     0.488
Lery_0373
Amino acid antiporter.
  
 
   0.449
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.445
lly
4-hydroxyphenylpyruvate dioxygenase.
     
 0.433
gadC
Glutamate/gamma-aminobutyrate antiporter.
  
 
   0.416
Lery_1992
UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
       0.413
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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