Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_1998GGDEF domain-containing protein. (436 aa)    
Predicted Functional Partners:
Lery_0948
Inner membrane protein/sensory box protein LssE.
  
  0.858
Lery_1999
Glutamate synthetase.
       0.840
stuC
Sensor histidine kinase.
 
0.829
Lery_2143
Sensory histidine-kinase / response regulator.
 
 0.822
Lery_0764
Signal transduction protein (EAL/GGDEF domain protein).
 
  
 0.821
Lery_0544
Regulatory protein (GGDEF and EAL domains).
  
   0.800
Lery_1248
Rtn protein.
  
    0.796
Lery_0932
Regulatory protein (EAL domain).
 
   
 0.791
Lery_2277
Two component histidine kinase.
  
  
 0.778
gacS/letS
Transmission sensor LetS.
 0.772
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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