lolC protein (Legionella erythra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lolC

Lipoprotein-releasing system transmembrane protein lolC. (414 aa)

Predicted Functional Partners:

lolD

0.997

Lery_1654

0.956

lolA

0.921

Lery_1653

0.878

Lery_2249

0.869

pal

0.806

bamA

0.788

lolB

0.760

Lery_2030

0.741

tolQ

0.609

Your Current Organism:

Legionella erythra

NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lery_1653	Lery_1654	Lery_1653	Lery_1654	ABC transporter permease.	ABC transporter ATP binding protein.	0.995
Lery_1653	Lery_2249	Lery_1653	Lery_2249	ABC transporter permease.	ABC transporter ATP-binding protein.	0.890
Lery_1653	lolA	Lery_1653	Lery_2127	ABC transporter permease.	Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.854
Lery_1653	lolB	Lery_1653	Lery_2528	ABC transporter permease.	Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.	0.723
Lery_1653	lolC	Lery_1653	Lery_2032	ABC transporter permease.	Lipoprotein-releasing system transmembrane protein lolC.	0.878
Lery_1653	lolD	Lery_1653	Lery_2031	ABC transporter permease.	ABC transporter ATP binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.986
Lery_1653	pal	Lery_1653	Lery_1733	ABC transporter permease.	Peptidoglycan-associated lipoprotein precursor (19 kDa surface antigen) (PPL); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	0.598
Lery_1654	Lery_1653	Lery_1654	Lery_1653	ABC transporter ATP binding protein.	ABC transporter permease.	0.995
Lery_1654	lolA	Lery_1654	Lery_2127	ABC transporter ATP binding protein.	Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.684
Lery_1654	lolC	Lery_1654	Lery_2032	ABC transporter ATP binding protein.	Lipoprotein-releasing system transmembrane protein lolC.	0.956
Lery_1654	lolD	Lery_1654	Lery_2031	ABC transporter ATP binding protein.	ABC transporter ATP binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.842
Lery_2030	lolC	Lery_2030	Lery_2032	Hypothetical protein.	Lipoprotein-releasing system transmembrane protein lolC.	0.741
Lery_2030	lolD	Lery_2030	Lery_2031	Hypothetical protein.	ABC transporter ATP binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.741
Lery_2249	Lery_1653	Lery_2249	Lery_1653	ABC transporter ATP-binding protein.	ABC transporter permease.	0.890
Lery_2249	lolA	Lery_2249	Lery_2127	ABC transporter ATP-binding protein.	Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.684
Lery_2249	lolC	Lery_2249	Lery_2032	ABC transporter ATP-binding protein.	Lipoprotein-releasing system transmembrane protein lolC.	0.869
Lery_2249	lolD	Lery_2249	Lery_2031	ABC transporter ATP-binding protein.	ABC transporter ATP binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.476
bamA	lolA	Lery_1295	Lery_2127	Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.767
bamA	lolB	Lery_1295	Lery_2528	Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	Molecular chaperone LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.	0.589
bamA	lolC	Lery_1295	Lery_2032	Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	Lipoprotein-releasing system transmembrane protein lolC.	0.788