Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fleRTwo-component response regulator. (433 aa)    
Predicted Functional Partners:
Lery_2125
Sensor kinase HydH.
 0.994
rpoN
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.942
Lery_0333
Flagellar biosynthesis MinD.
  
 
 0.906
Lery_0576
Sensory box histidine kinase/response regulator.
 
 0.875
Lery_2143
Sensory histidine-kinase / response regulator.
  
 0.865
fliE
Flagellar hook-basal body complex protein.
 
  
 0.863
stuC
Sensor histidine kinase.
  
 0.856
fliF
Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.790
fliG
Flagellar motor switch protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.788
Lery_2464
Response regulator receiver domain protein.
  
 0.784
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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