STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lery_2267AMP-binding protein. (554 aa)    
Predicted Functional Partners:
Lery_1668
Polyketide synthase module.
  
 0.895
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.871
Lery_1945
2-acylglycerophosphoethanolamine acyltransferase.
  
 
 0.849
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.841
pta_1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.813
pta_2
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.813
fadD-1
Long chain fatty acid-CoA ligase.
 
 
0.750
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.750
tenA
Thiaminase-2.
    
 0.712
Lery_2492
Putative aminoglycoside phosphotransferase.
   
 
 0.706
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.