Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilE_2Tfp pilus assembly protein, major type IV pilin class A. (168 aa)    
Predicted Functional Partners:
lspJ
Type II secretory pathway protein LspJ.
 
 0.825
Lery_2281
Inner membrane protein/sensory box protein LssE.
       0.796
lspE
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 0.768
pilB
Pilus assembly protein PilB.
 
 0.764
lspK
Type II secretory pathway protein LspK.
 
 
 0.759
lspF
Type II secretory pathway protein LspF.
 
  
 0.702
lspD
Type II protein secretion LspD.
 
 
 0.693
pilC
Pilus assembly protein PilC.
  
  
 0.647
lspG
Type II secretory pathway protein LspG.
  
     0.639
pilE_1
Type-IV pilin.
 
  
 0.535
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.