Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_2554Virulence protein. (207 aa)    
Predicted Functional Partners:
icmS
Protein IcmS.
    
 
 0.950
icmW
Intracellular multiplication protein IcmW.
    
 
 0.950
Lery_0480
Protein IcmO (DotL).
    
 
 0.812
rssA
Esterase of the alpha-beta hydrolase superfamily protein.
    
   0.775
Lery_2555
FeoC like transcriptional regulator.
       0.714
feoB
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
       0.714
feoA
Ferrous iron transporter A.
       0.714
dotD
Lipoprotein DotD.
      
 0.589
dotC
Defect in organelle trafficking lipoprotein DotC.
      
 0.589
Lery_2558
ATPase N2B (nucleotide (GTP) binding protein).
       0.586
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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