| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lery_2226 | birA | Lery_2226 | Lery_2931 | Rossmann-like domain protein. | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.470 |
| Lery_2226 | panB | Lery_2226 | Lery_2560 | Rossmann-like domain protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.887 |
| Lery_2226 | panC | Lery_2226 | Lery_2561 | Rossmann-like domain protein. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.942 |
| Lery_2226 | panD | Lery_2226 | Lery_1026 | Rossmann-like domain protein. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.460 |
| Lery_2555 | Lery_2558 | Lery_2555 | Lery_2558 | FeoC like transcriptional regulator. | ATPase N2B (nucleotide (GTP) binding protein). | 0.750 |
| Lery_2555 | Lery_2559 | Lery_2555 | Lery_2559 | FeoC like transcriptional regulator. | Alpha/beta superfamily transporter hydrolase. | 0.750 |
| Lery_2555 | feoB | Lery_2555 | Lery_2556 | FeoC like transcriptional regulator. | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | 0.907 |
| Lery_2555 | panB | Lery_2555 | Lery_2560 | FeoC like transcriptional regulator. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.643 |
| Lery_2555 | panC | Lery_2555 | Lery_2561 | FeoC like transcriptional regulator. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.597 |
| Lery_2558 | Lery_2555 | Lery_2558 | Lery_2555 | ATPase N2B (nucleotide (GTP) binding protein). | FeoC like transcriptional regulator. | 0.750 |
| Lery_2558 | Lery_2559 | Lery_2558 | Lery_2559 | ATPase N2B (nucleotide (GTP) binding protein). | Alpha/beta superfamily transporter hydrolase. | 0.866 |
| Lery_2558 | feoB | Lery_2558 | Lery_2556 | ATPase N2B (nucleotide (GTP) binding protein). | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | 0.750 |
| Lery_2558 | panB | Lery_2558 | Lery_2560 | ATPase N2B (nucleotide (GTP) binding protein). | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.704 |
| Lery_2558 | panC | Lery_2558 | Lery_2561 | ATPase N2B (nucleotide (GTP) binding protein). | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.666 |
| Lery_2559 | Lery_2555 | Lery_2559 | Lery_2555 | Alpha/beta superfamily transporter hydrolase. | FeoC like transcriptional regulator. | 0.750 |
| Lery_2559 | Lery_2558 | Lery_2559 | Lery_2558 | Alpha/beta superfamily transporter hydrolase. | ATPase N2B (nucleotide (GTP) binding protein). | 0.866 |
| Lery_2559 | feoB | Lery_2559 | Lery_2556 | Alpha/beta superfamily transporter hydrolase. | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | 0.750 |
| Lery_2559 | panB | Lery_2559 | Lery_2560 | Alpha/beta superfamily transporter hydrolase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.704 |
| Lery_2559 | panC | Lery_2559 | Lery_2561 | Alpha/beta superfamily transporter hydrolase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.666 |
| birA | Lery_2226 | Lery_2931 | Lery_2226 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Rossmann-like domain protein. | 0.470 |
