| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lery_1213 | Lery_2007 | Lery_1213 | Lery_2007 | Eukaryotic DNA topoisomerase I, catalytic core. | SNF2/RAD54 family transporter domain-containing protein. | 0.496 |
| Lery_1213 | dnaN | Lery_1213 | Lery_2814 | Eukaryotic DNA topoisomerase I, catalytic core. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.461 |
| Lery_1213 | polA | Lery_1213 | Lery_0793 | Eukaryotic DNA topoisomerase I, catalytic core. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.572 |
| Lery_1213 | recA | Lery_1213 | Lery_0135 | Eukaryotic DNA topoisomerase I, catalytic core. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.426 |
| Lery_1213 | recQ | Lery_1213 | Lery_2678 | Eukaryotic DNA topoisomerase I, catalytic core. | ATP-dependent DNA helicase RecQ. | 0.950 |
| Lery_1213 | topA | Lery_1213 | Lery_2487 | Eukaryotic DNA topoisomerase I, catalytic core. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.525 |
| Lery_1239 | Lery_2007 | Lery_1239 | Lery_2007 | Potassium efflux system KefA. | SNF2/RAD54 family transporter domain-containing protein. | 0.527 |
| Lery_1239 | dnaN | Lery_1239 | Lery_2814 | Potassium efflux system KefA. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.814 |
| Lery_1239 | holB | Lery_1239 | Lery_1195 | Potassium efflux system KefA. | DNA polymerase III subunit delta'. | 0.859 |
| Lery_1239 | polA | Lery_1239 | Lery_0793 | Potassium efflux system KefA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.977 |
| Lery_1239 | recA | Lery_1239 | Lery_0135 | Potassium efflux system KefA. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.948 |
| Lery_1239 | recQ | Lery_1239 | Lery_2678 | Potassium efflux system KefA. | ATP-dependent DNA helicase RecQ. | 0.984 |
| Lery_1239 | rep | Lery_1239 | Lery_0665 | Potassium efflux system KefA. | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. | 0.506 |
| Lery_1239 | topA | Lery_1239 | Lery_2487 | Potassium efflux system KefA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.939 |
| Lery_1239 | uvrD | Lery_1239 | Lery_0024 | Potassium efflux system KefA. | DNA helicase II. | 0.506 |
| Lery_2007 | Lery_1213 | Lery_2007 | Lery_1213 | SNF2/RAD54 family transporter domain-containing protein. | Eukaryotic DNA topoisomerase I, catalytic core. | 0.496 |
| Lery_2007 | Lery_1239 | Lery_2007 | Lery_1239 | SNF2/RAD54 family transporter domain-containing protein. | Potassium efflux system KefA. | 0.527 |
| Lery_2007 | dnaN | Lery_2007 | Lery_2814 | SNF2/RAD54 family transporter domain-containing protein. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.990 |
| Lery_2007 | holB | Lery_2007 | Lery_1195 | SNF2/RAD54 family transporter domain-containing protein. | DNA polymerase III subunit delta'. | 0.429 |
| Lery_2007 | polA | Lery_2007 | Lery_0793 | SNF2/RAD54 family transporter domain-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.991 |