Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Lery_2783RNA ligase/cyclic nucleotide phosphodiesterase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (186 aa)    
Predicted Functional Partners:
Lery_2782
Putative Dot/Icm substrate WipB.
       0.556
Lery_2781
Nucleotide pyrophosphohydrolase.
       0.552
treF
Alpha,alpha-trehalase.
     
  0.535
Lery_2780
Hypothetical protein.
       0.474
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.470
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.442
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.420
hisI
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
       0.407
Lery_0681
Hypothetical protein.
       0.402
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
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