Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lery_2826Lysophospholipase A. (358 aa)    
Predicted Functional Partners:
Lery_2827
Alpha helix protein; Belongs to the UPF0307 family.
       0.777
rlmL
Ribosomal RNA large subunit methyltransferase L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
       0.777
Lery_2825
Integral membrane protein.
       0.680
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.538
sdhA_2
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
      
 0.536
wrbA_2
Flavoprotein WrbA (Trp repressor binding protein).
       0.454
lspD
Type II protein secretion LspD.
   
  
 0.438
Lery_1110
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
      
 0.436
Lery_2823
Pirin-like protein; Belongs to the pirin family.
       0.435
lspK
Type II secretory pathway protein LspK.
      
 0.429
Your Current Organism:
Legionella erythra
NCBI taxonomy Id: 448
Other names: ATCC 35303, CCUG 29667, CIP 103843, DSM 17644, JCM 7564, L. erythra, NCTC 11977, strain SE-32A-C8
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.