| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ald | sce0063 | sce8152 | sce0063 | Alanine dehydrogenase; High confidence in function and specificity; Belongs to the AlaDH/PNT family. | Putative transcriptional regulator. | 0.901 |
| ald | sce0442 | sce8152 | sce0442 | Alanine dehydrogenase; High confidence in function and specificity; Belongs to the AlaDH/PNT family. | Serine-pyruvate aminotransferase; Family membership. | 0.905 |
| gcvP1 | gcvP2 | sce2012 | sce9164 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase (decarboxylating); Family membership. | 0.999 |
| gcvP1 | gcvT1 | sce2012 | sce2014 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvP1 | glnA1 | sce2012 | sce3953 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | GlnA1 protein; Family membership; Belongs to the glutamine synthetase family. | 0.830 |
| gcvP1 | glnA2 | sce2012 | sce7210 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glutamate--ammonia ligase; High confidence in function and specificity. | 0.830 |
| gcvP1 | glyA | sce2012 | sce6587 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.974 |
| gcvP1 | sce0063 | sce2012 | sce0063 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative transcriptional regulator. | 0.900 |
| gcvP1 | sce0442 | sce2012 | sce0442 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine-pyruvate aminotransferase; Family membership. | 0.901 |
| gcvP2 | gcvP1 | sce9164 | sce2012 | Glycine dehydrogenase (decarboxylating); Family membership. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
| gcvP2 | gcvT1 | sce9164 | sce2014 | Glycine dehydrogenase (decarboxylating); Family membership. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvP2 | glnA1 | sce9164 | sce3953 | Glycine dehydrogenase (decarboxylating); Family membership. | GlnA1 protein; Family membership; Belongs to the glutamine synthetase family. | 0.829 |
| gcvP2 | glnA2 | sce9164 | sce7210 | Glycine dehydrogenase (decarboxylating); Family membership. | Glutamate--ammonia ligase; High confidence in function and specificity. | 0.829 |
| gcvP2 | glyA | sce9164 | sce6587 | Glycine dehydrogenase (decarboxylating); Family membership. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.987 |
| gcvP2 | sce0063 | sce9164 | sce0063 | Glycine dehydrogenase (decarboxylating); Family membership. | Putative transcriptional regulator. | 0.904 |
| gcvP2 | sce0442 | sce9164 | sce0442 | Glycine dehydrogenase (decarboxylating); Family membership. | Serine-pyruvate aminotransferase; Family membership. | 0.914 |
| gcvT1 | gcvP1 | sce2014 | sce2012 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
| gcvT1 | gcvP2 | sce2014 | sce9164 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Glycine dehydrogenase (decarboxylating); Family membership. | 0.999 |
| gcvT1 | glnA1 | sce2014 | sce3953 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | GlnA1 protein; Family membership; Belongs to the glutamine synthetase family. | 0.826 |
| gcvT1 | glnA2 | sce2014 | sce7210 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | Glutamate--ammonia ligase; High confidence in function and specificity. | 0.826 |