STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sce0063Putative transcriptional regulator. (431 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.907
sce0442
Serine-pyruvate aminotransferase; Family membership.
  
 
 0.905
gcvP2
Glycine dehydrogenase (decarboxylating); Family membership.
   
 
 0.904
glnA1
GlnA1 protein; Family membership; Belongs to the glutamine synthetase family.
    
 0.903
glnA2
Glutamate--ammonia ligase; High confidence in function and specificity.
    
 0.903
gcvT1
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
  0.902
ald
Alanine dehydrogenase; High confidence in function and specificity; Belongs to the AlaDH/PNT family.
     
 0.901
sce0752
Putative glycolate oxidase; High confidence in function and specificity.
    
  0.900
kdgA1
KdgA1 protein; High confidence in function and specificity.
     
  0.900
gcvP1
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
     
  0.900
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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