STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvE1Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (296 aa)    
Predicted Functional Partners:
leuA1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 0.996
ilvD2
Dihydroxy-acid dehydratase; High confidence in function and specificity; Belongs to the IlvD/Edd family.
  
 0.967
sce3734
2-isopropylmalate synthase; Family membership; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.965
sce8481
Putative 2-isopropylmalate synthase; Family membership; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.965
leuA2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
 
 0.964
ilvA
Putative serine/threonine dehydratase; High confidence in function and specificity.
  
 
 0.935
sce6206
Glutamate/leucine/phenylalanine/valine dehydrogenase; Family membership; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.923
pdhB1
Pyruvate dehydrogenase (acetyl-transferring); High confidence in function and specificity.
  
 0.921
ilvE3
Branched-chain-amino-acid transaminase; High confidence in function and specificity.
 
   
 
0.921
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.920
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.