Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pflA2Pyruvate formate-lyase activating enzyme. (341 aa)    
Predicted Functional Partners:
sce1169
Alcohol dehydrogenase; Family membership.
 
  
 0.697
gbd
Alcohol dehydrogenase.
  
  
 0.651
nos
Nitric-oxide synthase, oxygenase subunit; Family membership.
  
  
 0.648
sce4484
Transketolase C-terminal-like domain.
 
   
 0.645
nasD
Nitrite reductase (NAD(P)H).
  
  
 0.519
nirB1
Nitrite reductase; High confidence in function and specificity; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.519
nirB2
Nitrite reductase; High confidence in function and specificity; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.519
pflA1
Pyruvate formate lyase activating enzyme; High confidence in function and specificity.
  
   
 0.499
sce5087
Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.471
sce3843
Hypothetical protein; COG: Predicted dioxygenase.
 
     0.461
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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