STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiGUroporphyrin-III C-methyltransferase; Family membership. (379 aa)    
Predicted Functional Partners:
cobM
Precorrin-3B C(17)-methyltransferase.
 
 0.999
cbiH
Precorrin-3B C(17)-methyltransferase; High confidence in function and specificity.
  
 0.999
cbiD
Cobalamin biosynthesis protein CbiD, probable; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 
 0.999
cobI
Precorrin-2-C20-methyltransferase; Family membership; Belongs to the precorrin methyltransferase family.
  
 0.995
cobH
CobH protein; Family membership.
 
  
 0.993
cobL
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); High confidence in function and specificity.
 
  
 0.980
cbiA
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.924
cbiM
Cobalamin biosynthesis integral membrane protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
 
  
 0.884
cbiX
Sirohydrochlorin cobaltochelatase; Function unclear.
 
   
 0.870
cbiP
Adenosylcobyric acid synthase (glutamine-hydrolyzing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.853
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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