STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobIPrecorrin-2-C20-methyltransferase; Family membership; Belongs to the precorrin methyltransferase family. (266 aa)    
Predicted Functional Partners:
cbiH
Precorrin-3B C(17)-methyltransferase; High confidence in function and specificity.
 
 0.999
cbiG
Uroporphyrin-III C-methyltransferase; Family membership.
  
 0.996
cobL
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); High confidence in function and specificity.
  
 0.995
cobH
CobH protein; Family membership.
 
  
 0.995
cbiD
Cobalamin biosynthesis protein CbiD, probable; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 0.995
cbiX
Sirohydrochlorin cobaltochelatase; Function unclear.
 
  
 0.980
cbiP
Adenosylcobyric acid synthase (glutamine-hydrolyzing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.974
hemD
Uroporphyrinogen-III synthase; Family membership.
 
  
 0.971
sce0393
Putative siroheme synthase; Family membership.
 
  
 0.951
cobM
Precorrin-3B C(17)-methyltransferase.
 
  
0.943
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.