Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cbiXSirohydrochlorin cobaltochelatase; Function unclear. (395 aa)    
Predicted Functional Partners:
sce0393
Putative siroheme synthase; Family membership.
  
 
 0.989
cobH
CobH protein; Family membership.
   
 0.981
cobI
Precorrin-2-C20-methyltransferase; Family membership; Belongs to the precorrin methyltransferase family.
 
  
 0.980
cbiO
Cobalt transport system, ATP-binding protein CbiO.
    
 0.976
cbiH
Precorrin-3B C(17)-methyltransferase; High confidence in function and specificity.
   
 0.966
hemD
Uroporphyrinogen-III synthase; Family membership.
 
  
 0.915
nuoE
NADH dehydrogenase (ubiquinone); High confidence in function and specificity.
 
 
 0.897
cbiG
Uroporphyrin-III C-methyltransferase; Family membership.
 
   
 0.879
cbiD
Cobalamin biosynthesis protein CbiD, probable; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
   
 0.875
cbiM
Cobalamin biosynthesis integral membrane protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
 0.866
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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