nnrE protein (Sorangium cellulosum So ce56) - STRING interaction network

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nnrE

ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...] (521 aa)

Predicted Functional Partners:

sce8276

0.919

sce5348

0.913

deaD1

0.843

deaD2

0.843

sce3615

0.843

deaD3

0.843

groL1

0.812

groL2

0.812

sce8304

0.697

glgP

0.694

Your Current Organism:

Sorangium cellulosum So ce56

NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
deaD1	deaD3	sce0700	sce5308	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	DeaD3 protein; High confidence in function and specificity.	0.922
deaD1	nnrE	sce0700	sce0321	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	0.843
deaD1	sce3615	sce0700	sce3615	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	Unnamed protein product; Family membership.	0.918
deaD1	sce5348	sce0700	sce5348	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	Hypothetical protein predicted by Glimmer/Critica.	0.539
deaD1	sce8276	sce0700	sce8276	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	ADP-ribose pyrophosphatase; Family membership.	0.570
deaD2	nnrE	sce3532	sce0321	DeaD2 protein; High confidence in function and specificity; Belongs to the DEAD box helicase family.	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	0.843
deaD2	sce5348	sce3532	sce5348	DeaD2 protein; High confidence in function and specificity; Belongs to the DEAD box helicase family.	Hypothetical protein predicted by Glimmer/Critica.	0.539
deaD2	sce8276	sce3532	sce8276	DeaD2 protein; High confidence in function and specificity; Belongs to the DEAD box helicase family.	ADP-ribose pyrophosphatase; Family membership.	0.570
deaD3	deaD1	sce5308	sce0700	DeaD3 protein; High confidence in function and specificity.	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	0.922
deaD3	nnrE	sce5308	sce0321	DeaD3 protein; High confidence in function and specificity.	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	0.843
deaD3	sce3615	sce5308	sce3615	DeaD3 protein; High confidence in function and specificity.	Unnamed protein product; Family membership.	0.925
deaD3	sce5348	sce5308	sce5348	DeaD3 protein; High confidence in function and specificity.	Hypothetical protein predicted by Glimmer/Critica.	0.539
deaD3	sce8276	sce5308	sce8276	DeaD3 protein; High confidence in function and specificity.	ADP-ribose pyrophosphatase; Family membership.	0.570
glgP	nnrE	sce4388	sce0321	Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	0.694
groL1	groL2	sce2781	sce5911	GroEL like chaperone, HSP60 family; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	Heat shock protein groEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.902
groL1	nnrE	sce2781	sce0321	GroEL like chaperone, HSP60 family; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	0.812
groL2	groL1	sce5911	sce2781	Heat shock protein groEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	GroEL like chaperone, HSP60 family; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.902
groL2	nnrE	sce5911	sce0321	Heat shock protein groEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	0.812
nnrE	deaD1	sce0321	sce0700	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	ATP-independent RNA helicase; High confidence in function and specificity; Belongs to the DEAD box helicase family.	0.843
nnrE	deaD2	sce0321	sce3532	ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...]	DeaD2 protein; High confidence in function and specificity; Belongs to the DEAD box helicase family.	0.843

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