Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce0400Alanine/proline-rich protein. (516 aa)    
Predicted Functional Partners:
sce0399
Hypothetical protein predicted by Glimmer/Critica.
       0.786
sce1177
Hypothetical protein predicted by Glimmer/Critica.
   
    0.549
sce0299
LysM domain-containing protein; Unnamed protein product; Function unclear.
   
    0.529
sce2093
Hypothetical protein predicted by Glimmer/Critica.
   
    0.529
otsA
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); High confidence in function and specificity.
   
    0.524
sce3268
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Family membership.
   
    0.524
lgt1
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.472
hisIE
Histidine biosynthesis bifunctional protein HisIE; Family membership; In the N-terminal section; belongs to the PRA-CH family.
       0.452
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.410
sce4451
DNA gyrase subunit A; High confidence in function and specificity.
  
    0.410
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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