| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceB | acs | sce8725 | sce7927 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.947 |
| aceB | bcpA | sce8725 | sce0599 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Carboxyvinyl-carboxyphosphonate phosphorylmutase; High confidence in function and specificity. | 0.792 |
| aceB | cis1 | sce8725 | sce1738 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Citrate synthase; Family membership; Belongs to the citrate synthase family. | 0.956 |
| aceB | cis2 | sce8725 | sce8281 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.956 |
| aceB | sce0442 | sce8725 | sce0442 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Serine-pyruvate aminotransferase; Family membership. | 0.929 |
| aceB | sce1736 | sce8725 | sce1736 | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | Citrate synthase (EC 2.3.3.1). | 0.958 |
| acnA | acs | sce8137 | sce7927 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.402 |
| acnA | bcpA | sce8137 | sce0599 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Carboxyvinyl-carboxyphosphonate phosphorylmutase; High confidence in function and specificity. | 0.558 |
| acnA | cis1 | sce8137 | sce1738 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Citrate synthase; Family membership; Belongs to the citrate synthase family. | 0.998 |
| acnA | cis2 | sce8137 | sce8281 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.996 |
| acnA | sce1736 | sce8137 | sce1736 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Citrate synthase (EC 2.3.3.1). | 0.998 |
| acs | aceB | sce7927 | sce8725 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | 0.947 |
| acs | acnA | sce7927 | sce8137 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.402 |
| acs | bcpA | sce7927 | sce0599 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Carboxyvinyl-carboxyphosphonate phosphorylmutase; High confidence in function and specificity. | 0.692 |
| acs | cis1 | sce7927 | sce1738 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; Family membership; Belongs to the citrate synthase family. | 0.946 |
| acs | cis2 | sce7927 | sce8281 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.946 |
| acs | sce1736 | sce7927 | sce1736 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase (EC 2.3.3.1). | 0.954 |
| bcpA | aceB | sce0599 | sce8725 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; High confidence in function and specificity. | Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family. | 0.792 |
| bcpA | acnA | sce0599 | sce8137 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; High confidence in function and specificity. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.558 |
| bcpA | acs | sce0599 | sce7927 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; High confidence in function and specificity. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.692 |